mrpB [2019-01-31 17:30:05]

Na⁺/H⁺ antiporter subunit, multiple resistance and pH homeostasis

Locus: BSU31610

Isoelectric point: 4.91

Molecular weight: 15.15 kDa

Protein length: 143 aa

Gene length: 432 bp

Function: sodium export

Product: Na⁺/H⁺ antiporter subunit

Essential: yes

Synonyms: yufU

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Metal ion transporter
• Cellular processes → Homeostasis → Metal ion homeostasis (K, Na, Ca, Mg) → Sodium uptake/ export
• Groups of genes → Essential genes
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,248,996 3,249,427

Phenotypes of a mutant

• essential PubMed

The protein

Structure

• 6CFW (corresponds to aa 1 ... 104, 31% identity)

Localization

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: mrpA-mrpB-mrpC-mrpD-mrpE-mrpF-mrpG
  Description: PubMed

Biological materials

Mutant

• MGNA-B558 (yufU::erm), available at the NBRP B. subtilis, Japan
• SM-GN9 (mrpB-spc), available in Anne Galinier's and Boris Grke's labs

References

Reviews

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Original publications

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