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catE [2018-11-01 12:43:49]
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catE [2018-11-01 12:43:49]

catechol 2,3-dioxygenase
locus
BSU08240
pI
5.30
mw
31.37 kDa
protein length
285 aa Sequence Blast
gene length
855 bp Sequence Blast
function
essential for the viability in the presence of catechol
product
catechol 2,3-dioxygenase
essential
no
synonyms
yfiE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

    • Gene

    Coordinates
    898,010 → 898,867

    Expression and Regulation

    Operons

    genes
    [gene|B7A0D1B3CAA2733A33BCCDDB6774ABF1A0223473|catD]-[gene|AA75013C05E1A88FC51410F9F1B30EE7D15F34C2|catE]
    description
    [Pubmed|16872404]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|20639328], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|YodB]: repression, [Pubmed|20639328], in [regulon|73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|YodB regulon]
  • [protein|5B9C4932B2E76D6B8F6BDB640D1ADEE28F488FAD|CatR]: repression, [Pubmed|20639328], in [regulon|5B9C4932B2E76D6B8F6BDB640D1ADEE28F488FAD|CatR regulon]
  • [protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]: repression, [pubmed|30377275], in [regulon|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur regulon]

    • regulation

  • strong induction by diamide and quinones (such as catechol) ([protein|73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|YodB], [protein|5B9C4932B2E76D6B8F6BDB640D1ADEE28F488FAD|CatR]) [Pubmed|16872404,20639328]
  • induced by iron starvation ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]) [pubmed|30377275]
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    Biological materials

    Mutant

  • MGNA-C295 (yfiE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2293 NBRP B. subtilis, Japan]
  • BKE08240 (Δ[gene|AA75013C05E1A88FC51410F9F1B30EE7D15F34C2|catE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGTCATGCTGCATGCCTCTT, downstream forward: _UP4_TAACTGCAATCCCCTTGCCG
  • BKK08240 (Δ[gene|AA75013C05E1A88FC51410F9F1B30EE7D15F34C2|catE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGTCATGCTGCATGCCTCTT, downstream forward: _UP4_TAACTGCAATCCCCTTGCCG

    • References

  • 17407181,16872404,20639328