nadD [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

nicotinamide-nucleotide adenylyltransferase

locus: BSU25640

pI: 5.00

mw: 22.00 kDa

function: NAD biosynthesis

product: nicotinamide-nucleotide adenylyltransferase

essential: yes

ec: 2.7.7.18

synonyms: yqeJ

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.11|Biosynthesis of NAD(P)]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of cofactors], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence): 2,643,765 -> 2,644,334

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• ATP nicotinate ribonucleotide = diphosphate deamido-NAD (according to Swiss-Prot)

Protein family

• nadD family (according to Swiss-Prot)

Structure

• [PDB|1KAQ]

Expression and Regulation

Operon

• ''[SW|yqeG]-[SW|yqeH]-[SW|aroD]-[SW|yqeI]-[SW|nadD]-[SW|yqeK]-[SW|yqeL]-[SW|yqeM]'' [Pubmed|22383849]

References

• 11704676,22383849