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upp [Mon Aug 31 2015 13:57:17 GMT+0200 (CEST)]
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upp [Mon Aug 31 2015 13:57:17 GMT+0200 (CEST)]

uracil phosphoribosyltransferase
locus
BSU36890
pI
5.86
mw
22.00 kDa
function
UMP synthesis
product
uracil phosphoribosyltransferase
essential
no
ec
2.4.2.9
synonyms
ipc-35d

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.4|Biosynthesis/ acquisition of pyrimidine nucleotides]
  • syns
    ipc-35d

    [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of nucleotides]
  • The protein

    Catalyzed reaction/ biological activity

  • UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
  • Protein family

  • UPRTase family (according to Swiss-Prot)
  • Structure

  • [PDB|2EHJ] (from ''Escherichia coli'', 52% identity, 73% similarity)
  • Expression and Regulation

    Operon

  • ''upp'' [Pubmed|9353933]
  • Biological materials

    Mutant

  • 1A832 (no resistance), [Pubmed|12366828], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A832&Search=1A832 BGSC]
  • References

  • 7798145