SubtiBank SubtiBank
upp
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

upp

uracil phosphoribosyltransferase
Locus
BSU_36890
Isoelectric point
5.86
Molecular weight
22.89 kDa
Protein length
209 aa Sequence Blast
Gene length
630 bp Sequence Blast
Function
UMP synthesis
Product
uracil phosphoribosyltransferase
Essential
no
E.C.
2.4.2.9
Synonyms
ipc-35d
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Metabolism → Nucleotide metabolism → Biosynthesis/ acquisition of nucleotides → Biosynthesis/ acquisition of pyrimidine nucleotides

    • Gene

    Coordinates
    3,788,426 3,789,055

    The protein

    Catalyzed reaction/ biological activity

  • diphosphate + UMP --> 5-phospho-α-D-ribose 1-diphosphate + uracil (according to UniProt)

    • Protein family

  • UPRTase family (single member, according to UniProt)

    • Structure

  • 2EHJ (from Escherichia coli, 52% identity, 73% similarity)

    • Expression and Regulation

    Operons

    Genes
    upp
    Description
    PubMed
    view in new tab

    Biological materials

    Mutant

  • 1A832 (no resistance), PubMed, available at BGSC
  • BKE36890 (upp::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACTGTGTTTCAGCTCCT, downstream forward: _UP4_TAAAAAATGAAATCCCCAAA
  • BKK36890 (upp::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACTGTGTTTCAGCTCCT, downstream forward: _UP4_TAAAAAATGAAATCCCCAAA

    • References

    Loading