natB

Na⁺ [SW|ABC transporter] (export) (ATP-binding protein)

locus: BSU_02760

pI: 5.36

mw: 42.63 kDa

protein length: 386 aa

gene length: 1161 bp

function: sodium export

product: Na⁺ [SW|ABC transporter] (export) (ATP-binding protein)

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.5|Export of ions]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.2|Sodium uptake/ export]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 297,170 298,330

The protein

Catalyzed reaction/ biological activity

• ATP + H₂O + Na⁺ --> ADP + H⁺ + Na⁺ + phosphate (according to UniProt)

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|B019FD0CB6F76C03DA5E76ABD1B324BA5E1A6936|natA]-[gene|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]
  description: [Pubmed|17322186]

  regulatory mechanism

  • [protein|D3F6337B94A633730E514B05CA852BE9AA3741B3|NatR]: activation, [Pubmed|17322186], in [regulon|D3F6337B94A633730E514B05CA852BE9AA3741B3|NatR regulon]

Biological materials

Mutant

• BKE02760 ([gene|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE02760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTTTTATAAATATGGCTCA, downstream forward: _UP4_TAAACTTGCGAAAGGAGAAA
• BKK02760 ([gene|A8ADA02BBB549866DE330040CF6D06ECC3B00099|natB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK02760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTTTTATAAATATGGCTCA, downstream forward: _UP4_TAAACTTGCGAAAGGAGAAA

References

• 9106203,10092453,17322186