SubtiBank SubtiBank
yxjG [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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yxjG [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

putative B12-independent methionine synthase
locus
BSU38960
pI
5.00
mw
42.00 kDa
function
unknown
product
putative methionine synthase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.11|Biosynthesis/ acquisition of methionine/ S-adenosylmethionine/ based on similarity]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of amino acids]

    • This gene is a member of the following [SW|regulons]

  • [SW|S-box]

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,999,350 -> 4,000,486

    The protein

    Paralogous protein(s)

  • [protein|search|YxjH]

    • Modification

  • S-bacillithiolation upon hypochlorite stress on Cys-346 [Pubmed|21749987]

    • Structure

  • [PDB|1YPX] (the enzyme from ''Listeria monocytogenes'', 49% identity)

    • Expression and Regulation

    Operon

  • ''yxjG'' [Pubmed|10746760]

    • Regulation

  • repressed by casamino acids [Pubmed|12107147]
  • induced by methionine starvation ([protein|search|S-box]) [Pubmed|10094622]

    • Regulatory mechanism

  • [protein|search|S-box]: transcription termination/ antitermination, the [protein|search|S-box] [SW|riboswitch] binds S-adenosylmethionine resulting in termination [Pubmed|10094622]

    • References

  • 19258532,10094622,18039762,12107147,21749987