nhaC [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

Na+/H+ antiporter

locus: BSU09680

pI: 7.87

mw: 47.00 kDa

function: pH homeostasis

product: Na+/H+ antiporter

essential: no

synonyms: yheL

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.2|Sodium uptake/ export]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.5|PH homeostasis]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|metal ion homeostasis (K, Na, Ca, Mg)], [SW|pH homeostasis], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 1,042,885 -> 1,044,246

The protein

Protein family

• nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|MleN]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|nhaC]'' [Pubmed|21815947]

Regulation

• subject to indirect positive regulation by [protein|search|CodY] [Pubmed|24843172]

Regulatory mechanism

• [protein|search|NhaX]: transcription activation (probably) [Pubmed|11274110]

Additional information

• the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] [PubMed|21815947]

References

• 11274110,21815947,24843172