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nhaC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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nhaC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

Na /H antiporter
locus
BSU09680
pI
7.00
mw
47.00 kDa
function
pH homeostasis
product
Na /H antiporter
essential
no
synonyms
yheL

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.2|Sodium uptake/ export]
  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.5|PH homeostasis]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|metal ion homeostasis (K, Na, Ca, Mg)], [SW|pH homeostasis], [SW|membrane proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,042,885 -> 1,044,246

    The protein

    Protein family

  • nhaC Na()/H() antiporter family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|MleN]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|nhaC]'' [Pubmed|21815947]
  • Regulation

  • subject to indirect positive regulation by [protein|search|CodY] [Pubmed|24843172]
  • Regulatory mechanism

  • [protein|search|NhaX]: transcription activation (probably) [Pubmed|11274110]
  • Additional information

  • the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] [PubMed|21815947]
  • Biological materials

    Mutant

  • MGNA-A707 (yheL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/707 NBRP B. subtilis, Japan]
  • References

  • 11274110,21815947,24843172