succinyl CoA:3-oxoacid CoA-transferase (subunit A)
function
3-hydroxybutyrate utilization
product
succinyl CoA:3-oxoacid CoA-transferase (subunit A)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.3|Utilization of fatty acids][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|SigE regulon]Gene
Coordinates on the chromosome (coding sequence)
4,001,976 -> 4,002,692
The protein
Catalyzed reaction/ biological activity
Succinyl-CoA a 3-oxo acid = succinate a 3-oxoacyl-CoA (according to Swiss-Prot)Protein family
3-oxoacid CoA-transferase subunit A family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|YodS]Structure
[PDB|3CDK] (the [SW|ScoA]-[SW|ScoB] complex)[SW|Interactions]
[SW|ScoA]-[SW|ScoB] [Pubmed|17363272]Expression and Regulation
Operon
''[protein|search|hbuT]-[protein|search|scoA]-[protein|search|scoB]-[protein|search|yxjF]'' [Pubmed|10746760][SW|Sigma factor]
[protein|search|SigE] [Pubmed|12662922]Regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|12850135,10666464]expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|12662922]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|12850135,10666464]References
17363272,10746760,16672620,12662922,12850135,10666464