SubtiBank SubtiBank
scoA
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scoA

succinyl CoA:3-oxoacid CoA-transferase (subunit A)
Locus
BSU_38990
Isoelectric point
6.61
Molecular weight
25.25 kDa
Protein length
238 aa Sequence Blast
Gene length
717 bp Sequence Blast
Function
3-hydroxybutyrate utilization
Product
succinyl CoA:3-oxoacid CoA-transferase (subunit A)
Essential
no
E.C.
2.8.3.5
Synonyms
yxjD

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
4,001,976 4,002,692

The protein

Catalyzed reaction/ biological activity

  • 3-oxo acid + succinyl-CoA --> 3-oxoacyl-CoA + succinate (according to UniProt)
  • Protein family

  • 3-oxoacid CoA-transferase subunit A family (with YodS, according to UniProt)
  • Paralogous protein(s)

    Structure

  • 3CDK (the ScoA-ScoB complex)
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon
  • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon
  • Regulation

  • expressed early during sporulation in the mother cell (SigE) PubMed
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    Biological materials

    Mutant

  • MGNA-B728 (yxjD::erm), available at the NBRP B. subtilis, Japan
  • BKE38990 (scoA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTGATGCCCCTTTCGT, downstream forward: _UP4_GCATCGGGAAAGGGTGAGGC
  • BKK38990 (scoA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTGATGCCCCTTTCGT, downstream forward: _UP4_GCATCGGGAAAGGGTGAGGC
  • References

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