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capA [2018-07-16 10:13:06]
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capA [2018-07-16 10:13:06]

capsular polyglutamate biosynthesis
Locus
BSU35880
Isoelectric point
9.27
Molecular weight
42.60 kDa
Protein length
380 aa Sequence Blast
Gene length
1140 bp Sequence Blast
Function
capsular polyglutamate biosynthesis
Product
unknown
Essential
no
Synonyms
ywtB,pgsA
Outlinks
KEGGBsubCycSubtiListUniProt

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Capsule biosynthesis and degradation

    • Gene

    Coordinates
    3,697,821 → 3,698,963

    Expression and Regulation

    Operons

    Genes
    capB-capC-capA-capE
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • DegU: activation, DegU-P, PubMed, in DegU regulon

    • Additional information

  • expression of the operon is increased in 'motA' or 'motB' mutants due to increased DegU phosphorylation PubMed
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    Biological materials

    Mutant

  • MGNA-B121 (pgsA::erm), available at the NBRP B. subtilis, Japan
  • BKE35880 (ΔcapA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTTCATCGTTTGACACACCT, downstream forward: _UP4_TCTAAATAATCGGAGTGATA
  • BKK35880 (ΔcapA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTTCATCGTTTGACACACCT, downstream forward: _UP4_TCTAAATAATCGGAGTGATA

    • References

    Reviews

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    Original publications

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