function
cell wall recycling
product
N-acetylglucosaminidase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.3|Utilization of cell wall components][SW|Categories] containing this gene/protein
[SW|cell wall degradation/ turnover], [SW|sporulation proteins]Gene
Coordinates on the chromosome (coding sequence)
186,452 -> 188,380
Phenotypes of a mutant
increased autolysis [Pubmed|20400549]The protein
Catalyzed reaction/ biological activity
cleaves muropeptides derived from peptidoglycan, but not peptidoglycan itself [Pubmed|20400549]Protein family
glycosyl hydrolase 3 family (according to Swiss-Prot)Structure
[PDB|3BMX] [Pubmed|20826810][SW|Localization]
secreted (with signal peptide), remains to some extent cell wall-associated [Pubmed|20400549]Additional information
The gene is mis-annotated in KEGG as an ortholog of beta-N-acetylhexosaminidase EC 3.2.1.52. It is marked in MetaCyc as “similar to beta-hexosaminidase”. No EC annotation is available in Swiss-ProtSwiss-Prot.supporting the annotation is available. [Pubmed|19935659]Expression and Regulation
Operon
''[protein|search|murQ]-[protein|search|murR]-[protein|search|murP]-[protein|search|amiE]-[protein|search|nagZ]-[protein|search|ybbC]'' [Pubmed|22383849]Regulation
expressed in late exponential and early stationary phase [Pubmed|20400549]Biological materials
Mutant
available in [SW|Christoph Mayer]'s lab [Pubmed|20400549]References
10627040,20400549,4628806,4196675,22383849 
