khtS

modulator of [protein|9A54C82323BA9220CAA6041E3745FAB9E222FE78|KhtU] activity

locus: BSU_09870

pI: 7.02

mw: 12.64 kDa

protein length: 112 aa

gene length: 339 bp

function: control of potassium ion efflux

product: modulator of [protein|9A54C82323BA9220CAA6041E3745FAB9E222FE78|KhtU] activity

essential: no

synonyms: yhaS

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.3|Potassium uptake/ export]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 1,060,988 1,061,326

The protein

[SW|Localization]

• cell membrane (peripheral, cytoplasmic side) [pubmed|14987767]

Expression and Regulation

Operons

• genes: [gene|A54E8E38AEF596D09B4BEB64D9F539A8AD34E73D|khtS]-[gene|D8A8FBC05B9665F72A88685D2B33822C2BB84C62|khtT]-[gene|9A54C82323BA9220CAA6041E3745FAB9E222FE78|khtU]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A681 ([gene|A54E8E38AEF596D09B4BEB64D9F539A8AD34E73D|khtS]::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/681 NBRP B. subtilis, Japan]
• GP2078 ([gene|A54E8E38AEF596D09B4BEB64D9F539A8AD34E73D|khtS]-[gene|D8A8FBC05B9665F72A88685D2B33822C2BB84C62|khtT]-[gene|9A54C82323BA9220CAA6041E3745FAB9E222FE78|khtU]::''aphA3''), available in [SW|Jörg Stülke]'s lab
• BKE09870 ([gene|A54E8E38AEF596D09B4BEB64D9F539A8AD34E73D|khtS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAGATATCCCTTCTTT, downstream forward: _UP4_TAATTTGCTCAAGTTTTATT
• BKK09870 ([gene|A54E8E38AEF596D09B4BEB64D9F539A8AD34E73D|khtS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAGATATCCCTTCTTT, downstream forward: _UP4_TAATTTGCTCAAGTTTTATT

References

• 14987767,24330391