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albE
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albE

antilisterial bacteriocin (subtilosin) production
locus
BSU_37410
pI
6.07
mw
43.20 kDa
protein length
386 aa Sequence Blast
gene length
1161 bp Sequence Blast
function
antilisterial bacteriocin (subtilosin) production
product
processing protease
essential
no
synonyms
ywhO
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds]

    • Gene

    Coordinates
    3,839,852 3,841,012

    Expression and Regulation

    Operons

    genes
    [gene|8CBBEC47A5CC3EAE73BE68E68417C5F2A4DA5C23|sboA]-[gene|83AAFAA187B4FCEE24B4EA2DD4935425A3B48DAA|sboX]-[gene|DEDA6F03386F360F6C0B2CC5F09DF3C9D85173F1|albA]-[gene|D399B25AE22ECB6C7ACDCFF4DCE4D9D908184E75|albB]-[gene|19CC58F5ABADAD45BA55D88BBD77B586AA5D85FE|albC]-[gene|DAD8308DF72E648610D1A12BC92063E1550CB1B4|albD]-[gene|A474F01AA4AD859963E39CD528BC42FF43A72433|albE]-[gene|D03FB4EAEFBC25A5B0459CF464BFADF1FC7620B2|albF]-[gene|55A34610EF7AA5E515DE3DCDA333ED3A42B0EF08|albG]
    description
    [Pubmed|10572140]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|10572140], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok]: repression, [Pubmed|15743949], in [regulon|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok regulon]
  • [protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD]: activation, [Pubmed|10809710], in [regulon|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [PubMed|10572140,17720793], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • expressed under anaerobic conditions ([protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD]) [Pubmed|10809710]
  • expression of the operon is strongly induced at the beginning of [SW|biofilm formation] [pubmed|31113899]
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    Biological materials

    Mutant

  • MGNA-A527 (ywhO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/527 NBRP B. subtilis, Japan]
  • BKE37410 ([gene|A474F01AA4AD859963E39CD528BC42FF43A72433|albE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37410 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGAAAATTGATGAGTCTTCA, downstream forward: _UP4_GCTCATGTAGTAAGGGGATG
  • BKK37410 ([gene|A474F01AA4AD859963E39CD528BC42FF43A72433|albE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37410 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGAAAATTGATGAGTCTTCA, downstream forward: _UP4_GCTCATGTAGTAAGGGGATG

    • References

  • 10809709,10572140,15743949,10809710,10572140,17720793