SubtiBank SubtiBank
yrhE [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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yrhE [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

unknown, similar to formate dehydrogenase
locus
BSU27220
pI
5.00
mw
108.00 kDa
function
unknown
product
unknown
essential
no
ec
1.2.1.2
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

    • [SW|Categories] containing this gene/protein

  • [SW|proteins of unknown function]

    • Gene

    Coordinates on the chromosome (coding sequence)
    2,781,209 -> 2,784,151

    The protein

    Catalyzed reaction/ biological activity

  • Formate NAD = CO2 NADH (according to Swiss-Prot)

    • [SW|Cofactors]

  • contains an iron-sulfur cluster

    • Additional information

  • The gene is annotated in KEGG as an ortholog of formate dehydrogenase EC 1.2.1.2. In Swiss-Prot the protein is named “formate dehydrogenase chain A”. In MetaCyc the protein is characterized as “similar to formate dehydrogenase”. No literature/experimental evidence supporting the annotation is available. [Pubmed|19935659]

    • Expression and Regulation

    Operon

  • ''[protein|search|yrhE]-[protein|search|yrhD]'' [Pubmed|21815947]

    • Additional information

  • the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] [PubMed|21815947]
  • term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of ''yrhE'' [Pubmed|27120414]

    • References

  • 21815947,27120414,19935659