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cssR [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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cssR [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

two-component response regulator (OmpR family), control of cellular responses to protein secretion stress
locus
BSU33010
pI
5.00
mw
26.00 kDa
function
control of cellular responses to protein secretion stress
product
two-component response regulator (OmpR family)
essential
no
synonyms
yvqA

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.4|Heat shock proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription factors and their control], [SW|heat shock proteins], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|CssR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,385,724 -> 3,386,401

    The protein

    Protein family

  • [SW|OmpR family] of two-component response regulators
  • Modification

  • phosphorylated by [protein|search|CssS] on an Asp residue
  • Effectors of protein activity

  • phosphorylation likely affects DNA-binding activity
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|CssR] interacts with the [SW|RNA polymerase] [Pubmed|21710567]
  • [protein|search|CssS]-[protein|search|CssR]
  • Expression and Regulation

    Operon

  • ''[protein|search|cssR]-[protein|search|cssS]'' [Pubmed|11555295]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|12270824]
  • Regulation

  • expressed under conditions of secretion stress ([protein|search|CssR]) [Pubmed|12270824]
  • Regulatory mechanism

  • [protein|search|CssR]: transcription activation [Pubmed|12270824]
  • References

    Reviews

  • 27518094
  • Original Publications

  • 10094672,17600057,21710567,17088376,12270824,12270824,11555295,19820159,21602801,21624103