two-component response regulator (OmpR family), control of cellular responses to protein secretion stress
function
control of cellular responses to protein secretion stress
product
two-component response regulator (OmpR family)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.4|Heat shock proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue][SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|heat shock proteins], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|CssR regulon]Gene
Coordinates on the chromosome (coding sequence)
3,385,724 -> 3,386,401
The protein
Protein family
[SW|OmpR family] of two-component response regulatorsModification
phosphorylated by [protein|search|CssS] on an Asp residueEffectors of protein activity
phosphorylation likely affects DNA-binding activity[SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|CssR] interacts with the [SW|RNA polymerase] [Pubmed|21710567][protein|search|CssS]-[protein|search|CssR]Expression and Regulation
Operon
''[protein|search|cssR]-[protein|search|cssS]'' [Pubmed|11555295][SW|Sigma factor]
[protein|search|SigA] [Pubmed|12270824]Regulation
expressed under conditions of secretion stress ([protein|search|CssR]) [Pubmed|12270824]Regulatory mechanism
[protein|search|CssR]: transcription activation [Pubmed|12270824]References
Reviews
Original Publications
10094672,17600057,21710567,17088376,12270824,12270824,11555295,19820159,21602801,21624103