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mpr [2019-06-18 09:14:12]
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mpr [2019-06-18 09:14:12]

extracellular metalloprotease
Locus
BSU02240
Isoelectric point
8.97
Molecular weight
33.69 kDa
Protein length
313 aa Sequence Blast
Gene length
942 bp Sequence Blast
Function
protein degradation
Product
extracellular metalloprotease
Essential
no
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
245,190 246,131

The protein

Protein family

  • peptidase S1B family (according to Swiss-Prot)
  • Structure

  • 1P3C (from B. intermedius, corresponds to aa 95 ... 289, 31% identity) PubMed
  • Localization

  • extracellular (signal peptide) PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Regulatory mechanism

  • CodY: repression, PubMed, in CodY regulon
  • Regulation

  • repressed by casamino acids PubMed
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    Biological materials

    Mutant

  • KO7 (nprE aprE epr mpr nprB vpr bpr), available as BGSC 1A1133
  • BKE02240 (mpr::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTGTCATCTCCCTCCT, downstream forward: _UP4_AACTTGGGAACAAGGGTGAC
  • BKK02240 (mpr::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTGTCATCTCCCTCCT, downstream forward: _UP4_AACTTGGGAACAAGGGTGAC
  • References

    Reviews

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    Original publications

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