ATPase, spore coat morphogenetic protein, anchors the spore coat to the spore surface via SpoVM
function
spore cortex formation and coat assembly
product
ATPase, basement layer protein for spore coat assembly
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.1|Class I][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue][SW|Categories] containing this gene/protein
[SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SpoIIID regulon]Gene
Phenotypes of a mutant
the spore coat does not localize to the spore surface but self-assembles into aggregates in the mother cell cytoplasm [Pubmed|22171814]The protein
Catalyzed reaction/ biological activity
uses ATP hydrolysis to drive self-assembly into static filaments [Pubmed|23267091]ATP hydrolysis drives polymerization of a nucleotide-free filament [Pubmed|23267091]ploymerization depends on a critical threshold concentration of SpoIVA that is only achieved once the protein is recruited to the surface of the developing spore [Pubmed|23267091][SW|Domains]
contains a Walker A ATPase domain[SW|Localization]
innermost protein of the spore coat basement [Pubmed|22171814][SW|Interactions]
[SW|SpoIVA]-[SW|SpoVID] [Pubmed|19702880,22262582][SW|SpoIVA]-[protein|search|SafA] [Pubmed|19702880,22262582][SW|SpoIVA]-[SW|SpoVM]-[SW|SpoVID] [Pubmed|19775244]Expression and Regulation
Operon
''spoIVA'' [Pubmed|1729246][SW|Sigma factor]
[protein|search|SigE] [Pubmed|1729246,15699190]Regulation
expressed early during sporulation in the mother cell ([protein|search|SigE], [SW|SpoIIID]) [Pubmed|1729246,15699190,15383836]Regulatory mechanism
[SW|SpoIIID]: transcription repression [Pubmed|15383836]References
Reviews
Original publications
8748030,15699190,1729246,8936302,1729247,9922240,7592342,8299942,1691789,12644503,18691972,17427285,19775244,22171814,15383836,23267091,19702880,22262582,24810258,25854653,26387458 
