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rapI [Mon Jan 04 2016 19:07:35 GMT+0100 (CET)]
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rapI [Mon Jan 04 2016 19:07:35 GMT+0100 (CET)]

response regulator aspartate phosphatase, antagonist of ImmR
locus
BSU05010
pI
5.00
mw
46.00 kDa
function
control of transfer of the mobile
genetic element ICEBs1
product
response regulator aspartate phosphatase
essential
no
synonyms
yddL

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.2|Response regulator aspartate phosphatase]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.7|Control of transcription factor (other than two-component system)]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing]
  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.2|Mobile genetic elements] → [category|SW 5.2.1|ICEBs1]
  • [SW|Categories] containing this gene/protein

  • [SW|protein modification], [SW|transcription factors and their control], [SW|quorum sensing], [SW|mobile genetic elements]
  • Gene

    Coordinates on the chromosome (coding sequence)
    547,306 -> 548,481

    The protein

    Catalyzed reaction/ biological activity

  • binds ImmR and inhibits its activity, this results in induction of the genes for the transfer of the mobile genetic element ICEBs1 [Pubmed|17511812]
  • Protein family

  • RAP family (according to Swiss-Prot)
  • Effectors of protein activity

  • binding of [protein|search|PhrI] indicates that neighbour cells do already contain the genetic element ICEBs1, this results in inactivation of RapI [Pubmed|17511812]
  • Structure

  • [PDB|4I1A] [Pubmed|23526881]
  • [SW|Interactions]

  • [protein|search|RapI]-[protein|search|ImmR] [Pubmed|17511812]
  • [protein|search|RapI]-[protein|search|PhrI] [Pubmed|17511812]
  • Expression and Regulation

    Operon

  • ''[protein|search|rapI]-[protein|search|phrI]'' [Pubmed|11466295]
  • References

    Reviews

  • 24995588
  • Original publications

  • 11466295,17511812,23526881