response regulator aspartate phosphatase, antagonist of ImmR
function
control of transfer of the mobile
genetic element ICEBs1
product
response regulator aspartate phosphatase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.2|Response regulator aspartate phosphatase][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.7|Control of transcription factor (other than two-component system)][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.2|Mobile genetic elements] → [category|SW 5.2.1|ICEBs1][SW|Categories] containing this gene/protein
[SW|protein modification], [SW|transcription factors and their control], [SW|quorum sensing], [SW|mobile genetic elements]Gene
Coordinates on the chromosome (coding sequence)
547,306 -> 548,481
The protein
Catalyzed reaction/ biological activity
binds ImmR and inhibits its activity, this results in induction of the genes for the transfer of the mobile genetic element ICEBs1 [Pubmed|17511812]Protein family
RAP family (according to Swiss-Prot)Effectors of protein activity
binding of [protein|search|PhrI] indicates that neighbour cells do already contain the genetic element ICEBs1, this results in inactivation of RapI [Pubmed|17511812]Structure
[PDB|4I1A] [Pubmed|23526881][SW|Interactions]
[protein|search|RapI]-[protein|search|ImmR] [Pubmed|17511812][protein|search|RapI]-[protein|search|PhrI] [Pubmed|17511812]Expression and Regulation
Operon
''[protein|search|rapI]-[protein|search|phrI]'' [Pubmed|11466295]References
Reviews
Original publications
11466295,17511812,23526881