SubtiBank SubtiBank
uxaB
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uxaB

tagaturonate reductase
Locus
BSU_12380
Isoelectric point
5.06
Molecular weight
55.19 kDa
Protein length
480 aa Sequence Blast
Gene length
1443 bp Sequence Blast
Function
hexuronate utilization
Product
tagaturonate reductase
Essential
no
E.C.
1.1.1.58
Synonyms
yjmI

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,309,880 1,311,322

The protein

Catalyzed reaction/ biological activity

  • D-altronate + NAD+ --> keto-D-tagaturonate + NADH (according to UniProt)
  • Protein family

  • mannitol dehydrogenase family (with MtlD, according to UniProt)
  • Structure

  • 4IM7 (YdfI from E. coli, aa 1 - 370, 26% identity)
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigE: sigma factor, PubMed, in SigE regulon
  • Regulatory mechanism

  • ExuR: repression, in the absence of inducer, in ExuR regulon
  • CcpA: repression, PubMed PubMed, in CcpA regulon
  • Regulation

  • induced by galacturonate (ExuR) PubMed
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    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • ExuR: repression, in the absence of inducer, in ExuR regulon
  • CcpA: repression, PubMed PubMed, in CcpA regulon
  • Regulation

  • induced by galacturonate (ExuR) PubMed
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    Biological materials

    Mutant

  • MGNA-A373 (yjmI::erm), available at the NBRP B. subtilis, Japan
  • BKE12380 (uxaB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACCCTTATTGCCTCCCTCT, downstream forward: _UP4_TGCATACAAGGGGGAGAGGT
  • BKK12380 (uxaB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACCCTTATTGCCTCCCTCT, downstream forward: _UP4_TGCATACAAGGGGGAGAGGT
  • References

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