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ldh [Mon Aug 31 2015 13:52:14 GMT+0200 (CEST)]
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ldh [Mon Aug 31 2015 13:52:14 GMT+0200 (CEST)]

L-lactate dehydrogenase
Locus
BSU03050
Isoelectric point
5.39
Molecular weight
34.00 kDa
Function
overflow metabolism, fermentation
Product
L-lactate dehydrogenase
Essential
no
E.C.
1.1.1.27
Synonyms
lctE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Carbon core metabolism → Overflow metabolism
  • Groups of genes → Phosphoproteins → Phosphorylation on a Tyr residue
    • Syns
    lctE

    Categories containing this gene/protein

  • carbon core metabolism, phosphoproteins

    • This gene is a member of the following regulons

  • Rex regulon

    • The protein

    Catalyzed reaction/ biological activity

  • (S)-lactate + NAD+ = pyruvate + NADH (according to Swiss-Prot)

    • Protein family

  • LDH family (according to Swiss-Prot)

    • Modification

  • phosphorylation on Tyr-224 PubMed

    • Structure

  • 3PQE
  • [PDB|A general discussion of Ldh structure]

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Interactions

  • forms tetramers PubMed

    • Expression and Regulation

    Operon

  • ldh-lctP PubMed

    • Sigma factor

  • SigA PubMed

    • Regulation

  • induced under anaerobic conditions (Rex) PubMed

    • Regulatory mechanism

  • Rex: transcription repression PubMed

    • References

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