SubtiBank SubtiBank
ypgQ
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ypgQ

Mn2+-dependent pyrophosphohydrolase, hydrolyzes (deoxy)ribonucleoside triphosphate [(d)NTP] to (deoxy)ribonucleoside monophosphate and pyrophosphate
Locus
BSU_21890
Isoelectric point
5.51
Molecular weight
22.98 kDa
Protein length
205 aa Sequence Blast
Gene length
618 bp Sequence Blast
Function
degradation of excessive or abnormal nucleotides
Product
Mn2+-dependent pyrophosphohydrolase
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Nucleotide metabolism → Nucleotide metabolism/ other

    • Gene

    Coordinates
    2,303,920 2,304,537

    The protein

    Domains

  • HD domain (aa 22-138) PubMed

    • Cofactors

  • Mn2+ PubMed

    • Structure

  • 5IHY PubMed
  • 5DQV PubMed
  • 5DQW (complexed with ADP) PubMed

    • Expression and Regulation

    Operons

    Genes
    bsaA-ypgQ-ypgR
    Description
    PubMed
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    Biological materials

    Mutant

  • MGNA-A888 (ypgQ::erm), available at the NBRP B. subtilis, Japan
  • BKE21890 (ypgQ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTCCTTCACAAAAACACCCT, downstream forward: _UP4_TAATAGAAGGCTTGGAGCGA
  • BKK21890 (ypgQ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTCCTTCACAAAAACACCCT, downstream forward: _UP4_TAATAGAAGGCTTGGAGCGA

    • References

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