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srtN [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
protein deacetylase for the control of AcsA activity
function
control of AcsA activity
product
NAD( )-dependent AcsA deacetylase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.5|Protein acetylases/ deacetylases][SW|Categories] containing this gene/protein
[SW|protein modification]Gene
Coordinates on the chromosome (coding sequence)
1,040,094 -> 1,040,837
The protein
Catalyzed reaction/ biological activity
NAD an acetylprotein = nicotinamide O-acetyl-ADP-ribose a protein (according to Swiss-Prot) deacetylates (and thereby activates) [protein|search|AcsA] (together with [protein|search|AcuC]) [Pubmed|19136592]Protein family
deacetylase sirtuin-type domain (according to Swiss-Prot)Structure
[PDB|1MA3] (from ''Archaeoglobus fulgidus'', 40% identity) [Pubmed|12408821][SW|Localization]
cytoplasm (according to Swiss-Prot)Biological materials
Mutant
GP1210 (''[protein|search|srtN]''::''cat''), available in [SW|Jörg Stülke]'s lab1A888 ( ''srtN''::''spec''), [Pubmed|19136592], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A888&Search=1A888 BGSC]References
19136592,26708127,12408821,26098117