SubtiBank SubtiBank
srtN [2017-09-16 18:35:08]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

srtN [2017-09-16 18:35:08]

protein deacetylase for the control of AcsA activity
locus
BSU09650
pI
5.13
mw
27.27 kDa
protein length
247 aa Sequence Blast
gene length
741 bp Sequence Blast
function
control of AcsA activity
product
NAD( )-dependent AcsA deacetylase
essential
no
synonyms
yhdZ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.5|Protein acetylases/ deacetylases]

    • Gene

    Coordinates
    1,040,094 → 1,040,837

    The protein

    Catalyzed reaction/ biological activity

  • NAD an acetylprotein = nicotinamide O-acetyl-ADP-ribose a protein (according to Swiss-Prot) deacetylates (and thereby activates) [protein|6671E7D85E99D349679F0E9D825DC035D10FFD2E|AcsA] (together with [protein|1255813797A83D835E0656A2AAAD361B5BB2094B|AcuC]) [Pubmed|19136592]

    • Protein family

  • deacetylase sirtuin-type domain (according to Swiss-Prot)

    • Structure

  • [PDB|1MA3] (from ''Archaeoglobus fulgidus'', 40% identity) [Pubmed|12408821]

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|A0A6CB19191A251BB5600C18E039978A9A34933C|srtN]
    description
    [Pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-B488 (yhdZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1487 NBRP B. subtilis, Japan]
  • GP1210 (''[gene|A0A6CB19191A251BB5600C18E039978A9A34933C|srtN]''::''cat''), available in [SW|Jörg Stülke]'s lab
  • 1A888 ( ''srtN''::''spec''), [Pubmed|19136592], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A888&Search=1A888 BGSC]
  • BKE09650 (Δ[gene|A0A6CB19191A251BB5600C18E039978A9A34933C|srtN]::erm trpC2), available at [http://www.bgsc.org/getdetail.php?bgscid=BSU09650 BGSC], upstream reverse: 
    _UP1_CAACTCAACACCGCCTTTTT
    , downstream forward: 
    _UP4_TGAGCCGCTTTATGCGCCTC
  • BKK09650 (Δ[gene|A0A6CB19191A251BB5600C18E039978A9A34933C|srtN]::kan trpC2), available at [http://www.bgsc.org/getdetail.php?bgscid=BSU09650 BGSC], upstream reverse: 
    _UP1_CAACTCAACACCGCCTTTTT
    , downstream forward: 
    _UP4_TGAGCCGCTTTATGCGCCTC

    • References

  • 19136592,26708127,12408821,26098117