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srtN [2017-09-16 18:35:08]
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srtN [2017-09-16 18:35:08]

protein deacetylase for the control of AcsA activity
Locus
BSU09650
Isoelectric point
5.13
Molecular weight
27.27 kDa
Protein length
247 aa Sequence Blast
Gene length
741 bp Sequence Blast
Function
control of AcsA activity
Product
NAD( )-dependent AcsA deacetylase
Essential
no
Synonyms
yhdZ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Protein modification → Protein acetylases/ deacetylases

    • Gene

    Coordinates
    1,040,094 → 1,040,837

    The protein

    Catalyzed reaction/ biological activity

  • NAD an acetylprotein = nicotinamide O-acetyl-ADP-ribose a protein (according to Swiss-Prot) deacetylates (and thereby activates) AcsA (together with AcuC) PubMed

    • Protein family

  • deacetylase sirtuin-type domain (according to Swiss-Prot)

    • Structure

  • 1MA3 (from Archaeoglobus fulgidus, 40% identity) PubMed

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    srtN
    Description
    PubMed
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    Biological materials

    Mutant

  • MGNA-B488 (yhdZ::erm), available at the NBRP B. subtilis, Japan
  • GP1210 (srtN::cat), available in Jörg Stülke's lab
  • 1A888 ( srtN::spec), PubMed, available at BGSC
  • BKE09650 (ΔsrtN::erm trpC2), available at BGSC, upstream reverse: 
    _UP1_CAACTCAACACCGCCTTTTT
    , downstream forward: 
    _UP4_TGAGCCGCTTTATGCGCCTC
  • BKK09650 (ΔsrtN::kan trpC2), available at BGSC, upstream reverse: 
    _UP1_CAACTCAACACCGCCTTTTT
    , downstream forward: 
    _UP4_TGAGCCGCTTTATGCGCCTC

    • References

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