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ktrD [2017-07-03 14:35:57]
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ktrD [2017-07-03 14:35:57]

low affinity potassium transporter KtrC-KtrD, integral membrane subunit
locus
BSU13500
pI
9.22
mw
49.26 kDa
protein length
449 aa Sequence Blast
gene length
1347 bp Sequence Blast
function
potassium uptake
product
low affinity potassium transporter KtrC-KtrD, integral membrane subunit (proton symport)
essential
no
synonyms
ykrM
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.3|Potassium uptake/ export]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,416,067 → 1,417,416

    The protein

    Protein family

  • View classification (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|A287B9771A56D03ADCA603C1969CBF03DCB10E95|KtrB]

    • Structure

  • [PDB|4J7C] (the [protein|92D0275E0768780F782F4B3724BC5181E436B6B1|KtrA]-[protein|A287B9771A56D03ADCA603C1969CBF03DCB10E95|KtrB] complex, 36% identity) [Pubmed|23598340]

    • [SW|Localization]

  • integral membrane protein [Pubmed|12562800]

    • Expression and Regulation

    Operons

    genes
    [gene|A0952B75E5BD0D09B0F4C257822428640998558B|ktrD]
    description
    [Pubmed|12562800]

    regulation

  • constitutively expressed
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B317 (ykrM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1316 NBRP B. subtilis, Japan]
  • GHB12 (''ktrD''::''tet''), [Pubmed|12562800], available in [SW|Erhard Bremer]'s and [SW|Jörg Stülke]'s labs
  • GP2030 (''ktrD''::''tet''), available in [SW|Jörg Stülke]'s lab [pubmed|28420751]
  • 1A956 (''ktrD''::''tet''), [Pubmed|12562800], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A956&Search=1A956 BGSC]

    • FLAG-tag construct

  • GP2434 ''ktrD-3xFLAG spc'' (based on [SW|pGP1331]), available in [SW|Jörg Stülke]'s lab

    • Labs working on this gene/protein

  • [SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]

    • References

    Reviews

  • 21680052,27935846

    • Original publications

  • 12562800,23598340,28420751