ktrD [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

low affinity potassium transporter KtrC-KtrD, integral membrane subunit

locus: BSU13500

pI: 9.00

mw: 49.00 kDa

function: potassium uptake

product: low affinity potassium transporter KtrC-KtrD,
integral membrane subunit (proton symport)

essential: no

synonyms: ykrM

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.3|Potassium uptake/ export]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|metal ion homeostasis (K, Na, Ca, Mg)], [SW|coping with hyper-osmotic stress], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 1,416,067 -> 1,417,416

The protein

Protein family

• View classification (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|KtrB]

Structure

• [PDB|4J7C] (the [protein|search|KtrA]-[protein|search|KtrB] complex, 36% identity) [Pubmed|23598340]

[SW|Localization]

• integral membrane protein [Pubmed|12562800]

[SW|Interactions]

• [protein|search|KtrC]-[protein|search|KtrD] [Pubmed|12562800]

Expression and Regulation

Operon

• ''ktrD'' [Pubmed|12562800]

Regulation

• constitutively expressed

Biological materials

Mutant

• MGNA-B317 (ykrM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1316 NBRP B. subtilis, Japan]
• GHB12 (''ktrD''::''tet''), [Pubmed|12562800], available in [SW|Erhard Bremer]'s and [SW|Jörg Stülke]'s labs
• GP2030 (''ktrD''::''tet''), available in [SW|Jörg Stülke]'s lab
• 1A956 (''ktrD''::''tet''), [Pubmed|12562800], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A956&Search=1A956 BGSC]

Labs working on this gene/protein

• [SW|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]

References

Reviews

• 21680052

Original publications

• 12562800,23598340