SubtiBank SubtiBank
ylxS
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ylxS

similar to ribosome maturation protein
locus
BSU_16590
pI
4.48
mw
17.48 kDa
protein length
156 aa Sequence Blast
gene length
471 bp Sequence Blast
function
ribosome maturation
product
unknown
essential
no
synonyms
ymxA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.13|Translation/ other/ based on similarity]

    • Gene

    Coordinates
    1,731,776 1,732,246

    The protein

    Protein family

  • RimP family (single member, according to UniProt)

    • Structure

  • [PDB|1IB8] (from ''Streptococcus pneumoniae'', 41% identity) [Pubmed|11493012]

    • Expression and Regulation

    Operons

    genes
    [gene|9F6C447900410BF64409E5C41A11C76968DADAFA|ylxS]-[gene|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA]-[gene|F4097349A563503468A2A14F062AEAC532C7917A|ylxR]-[gene|7BFA65857F69855DBB3BB64D93B4ED2F09DC705B|rplGA]-[gene|378B77412D0DEA220A97DEC246410509D9B74D46|infB]-[gene|24835CE6CD2E1F183DB9121F29A63101718B5DF9|ylxP]-[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]
    description
    [Pubmed|8491709]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8491709], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528,26577401], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]
  • [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA]: attenuation, [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA] stimulates termination [Reference|http://www.nature.com/articles/nmicrobiol20157], in [regulon|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA regulon]

    • regulation

  • autoregulation [SW|NusA] [http://www.nature.com/articles/nmicrobiol20157 reference]
  • induced by glucose [pubmed|30355672]
    • view in new tab

    Biological materials

    Mutant

  • BKE16590 ([gene|9F6C447900410BF64409E5C41A11C76968DADAFA|ylxS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16590 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTCTTCCTCCTTGTGC, downstream forward: _UP4_TAATGAATACAAATGTTTTA
  • BKK16590 ([gene|9F6C447900410BF64409E5C41A11C76968DADAFA|ylxS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16590 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTCTTCCTCCTTGTGC, downstream forward: _UP4_TAATGAATACAAATGTTTTA

    • References

  • 11948165,8491709,20525796,19150615,11493012,27120414