SubtiBank SubtiBank
spoIIR [Mon Aug 31 2015 13:57:18 GMT+0200 (CEST)]
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spoIIR [Mon Aug 31 2015 13:57:18 GMT+0200 (CEST)]

required for processing and compartmentalization of pro-SigE
locus
BSU36970
pI
4.74
mw
25.00 kDa
function
control of SigE activation
product
morphological chekcpoint for SigE processing
essential
no
synonyms
ipc-27d, csfX

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • syns
    ipc-27d, csfX

    [SW|Categories] containing this gene/protein

  • [SW|sigma factors and their control], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigF regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • interacts with and activates the pro-[protein|search|SigE] protease [SW|SpoIIGA] in the intermembrane space between the forespore and the mother cell [Pubmed|22111992]
  • Modification

  • likely acylated on Thr-27 [Pubmed|22111992]
  • [SW|Localization]

  • localizes initially to the forespore septal membrane (in a [SW|SpoIIGA]-dependent manner), is then exported to the intermembrane space between the forespore and the mother cell [Pubmed|22111992]
  • [SW|Interactions]

  • [SW|SpoIIR]-[SW|SpoIIGA] [Pubmed|22111992]
  • Expression and Regulation

    Operon

  • spoIIR (according to [http://dbtbs.hgc.jp/COG/prom/spoIIR.html DBTBS])
  • [SW|Sigma factor]

  • [protein|search|SigF] [Pubmed|16497325]
  • Regulation

  • expressed early during sporulation in the forespore ([protein|search|SigF]) [Pubmed|16497325,15699190]
  • References

  • 16497325,7585939,15044948,11849534,19578359