required for processing and compartmentalization of pro-SigE
function
control of SigE activation
product
morphological chekcpoint for SigE processing
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|sigma factors and their control], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigF regulon]The protein
Catalyzed reaction/ biological activity
interacts with and activates the pro-[protein|search|SigE] protease [SW|SpoIIGA] in the intermembrane space between the forespore and the mother cell [Pubmed|22111992]Modification
likely acylated on Thr-27 [Pubmed|22111992][SW|Localization]
localizes initially to the forespore septal membrane (in a [SW|SpoIIGA]-dependent manner), is then exported to the intermembrane space between the forespore and the mother cell [Pubmed|22111992][SW|Interactions]
[SW|SpoIIR]-[SW|SpoIIGA] [Pubmed|22111992]Expression and Regulation
Operon
spoIIR (according to [http://dbtbs.hgc.jp/COG/prom/spoIIR.html DBTBS])[SW|Sigma factor]
[protein|search|SigF] [Pubmed|16497325]Regulation
expressed early during sporulation in the forespore ([protein|search|SigF]) [Pubmed|16497325,15699190]References
16497325,7585939,15044948,11849534,19578359