component of the SpoIIIA-SpoIIQ type III secretion system residing in the forespore membrane, required for SigG activation
function
activation of SigG
product
component of a type III secretion system
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|protein secretion], [SW|sporulation proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SpoIIID regulon]The protein
[SW|Localization]
membrane protein [Pubmed|18485064], insertion into the membrane requires [SW|SpoIIIJ] [Pubmed|18485064][SW|Interactions]
[SW|SpoIIIAE]-[SW|SpoIIIJ] (in membrane)[Pubmed|18820020]Expression and Regulation
Operon
''[SW|spoIIIAA]-[SW|spoIIIAB]-[SW|spoIIIAC]-[SW|spoIIIAD]-[SW|spoIIIAE]-[SW|spoIIIAF]-[SW|spoIIIAG]-[SW|spoIIIAH]'' [Pubmed|18485064][SW|Sigma factor]
[protein|search|SigE] [Pubmed|15699190,18485064]Regulation
expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|18485064], switched off by [SW|SpoIIID] [Pubmed|15383836]Regulatory mechanism
[SW|SpoIIID]: transcription repression [Pubmed|15383836]Labs working on this gene/protein
[SW|Richard Losick], Harvard University, Cambridge, USA [http://www.mcb.harvard.edu/Losick/ homepage][SW|Adriano Henriques], Lisbon, Portugal [http://www.itqb.unl.pt/research/biology/microbial-development homepage]References
1766372,18485064,18820020,19609349 
