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drm [Mon Aug 31 2015 13:55:25 GMT+0200 (CEST)]
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drm [Mon Aug 31 2015 13:55:25 GMT+0200 (CEST)]

phosphopentomutase
locus
BSU23500
pI
4.97
mw
43.00 kDa
function
utilization of deoxyribose
product
phosphopentomutase
essential
no
ec
5.4.2.7
synonyms
yqkN

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.6|Phosphorylation on a Thr residue]
  • syns
    yqkN

    [SW|Categories] containing this gene/protein

  • [SW|utilization of nucleotides], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate (according to Swiss-Prot)
  • Protein family

  • phosphopentomutase family (according to Swiss-Prot)
  • Modification

  • phosphorylation on (Thr-87 OR Thr-89) [Pubmed|17218307,17726680]
  • Structure

  • [PDB|3M8W] (from ''B. cereus'', 77% identity, 86% similarity) [Pubmed|21193409]
  • Expression and Regulation

    Operon

  • ''[protein|search|drm]-[protein|search|pupG]'' [Pubmed|10537218]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|10537218]
  • Regulation

  • induced in the presence of nucleosides (deoxyribose 5-phosphate and ribose 5-phosphate act as molecular inducers) [Pubmed|10537218]
  • subject to carbon catabolite repression ([protein|search|CcpA]) [Pubmed|22900538,10537218]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|22900538]
  • References

  • 10537218,17218307,17726680,22900538