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ileS
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ileS

isoleucyl-tRNA synthetase
Locus
BSU_15430
Isoelectric point
5.19
Molecular weight
104.58 kDa
Protein length
921 aa Sequence Blast
Gene length
2766 bp Sequence Blast
Function
translation
Product
isoleucyl-tRNA synthetase
Essential
yes
E.C.
6.1.1.5
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,613,357 1,616,122

Phenotypes of a mutant

  • essential PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • ATP + L-isoleucine + tRNAIle --> AMP + diphosphate + L-isoleucyl-tRNAIle (according to UniProt)
  • Protein family

    Structure

  • 1QU2 (from Staphylococcus aureus, 61% identity) PubMed
  • Localization

  • cytoplasm (according to Swiss-Prot)
  • Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Regulatory mechanism

  • T-box: antitermination, PubMed, in T-box
  • Regulation

  • induced by isoleucine limitation (T-box) PubMed
  • the T-box RNA is degraded by RNase Y PubMed
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    References

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