yokJ [2018-11-19 18:00:48]

putative antitoxin

locus: BSU21570

pI: 4.13

mw: 18.76 kDa

protein length: 165 aa

gene length: 495 bp

function: inhibition of the cytotoxic activity of YokI

product: putative antitoxin

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.2|Type 2 TA systems]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.18|Toxins, antitoxins and immunity against toxins/ based on similarity]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]

Gene

Coordinates: 2,275,200 → 2,275,697

Expression and Regulation

Operons

• genes: [gene|13C081250872E72C61C49D8F77AC5AF4B6D431A3|yokI]-[gene|9BC2309D7FC93CD4195849BFCF195ED3EBC3CAF1|yokJ]-[gene|8BA8DB1483190AB847F28F3E56C247FE85C3225E|yokK]-[gene|9A03964C94A9253B3D9AAA60ACA0651AED49A627|yokL]
  description: [Pubmed|20817675]

  regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

  additional information

  • A [protein|search|ncRNA] is predicted between '[protein|search|yolA]' and '[protein|search|yokL]' [PubMed|20525796]

Biological materials

Mutant

• BKE21570 (Δ[gene|9BC2309D7FC93CD4195849BFCF195ED3EBC3CAF1|yokJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAATGCTCAAGTCCG, downstream forward: _UP4_TAATCTATTAAACAAAAGTA
• BKK21570 (Δ[gene|9BC2309D7FC93CD4195849BFCF195ED3EBC3CAF1|yokJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAATGCTCAAGTCCG, downstream forward: _UP4_TAATCTATTAAACAAAAGTA

References

• 22200572,20817675