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thiM [Mon Aug 31 2015 13:57:28 GMT+0200 (CEST)]
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thiM [Mon Aug 31 2015 13:57:28 GMT+0200 (CEST)]

hydroxyethylthiazole kinase
locus
BSU38300
pI
5.39
mw
28.00 kDa
function
biosynthesis of thiamine
product
hydroxyethylthiazole kinase
essential
no
ec
2.7.1.50
synonyms
thiK, ipa-25d, ywbJ

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.3|Biosynthesis/ acquisition of thiamine]
  • syns
    thiK, ipa-25d, ywbJ

    [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole (according to Swiss-Prot)
  • Protein family

  • Thz kinase family (according to Swiss-Prot)
  • Structure

  • [PDB|1C3Q]
  • [SW|Interactions]

  • [protein|search|ThiM]-[protein|search|ThiM] [Pubmed|10891066]
  • Expression and Regulation

    Operon

  • ''[protein|search|ywbI]-[protein|search|thiM]-[protein|search|thiE]'' [Pubmed|9139923]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9139923]
  • References

    Reviews

  • 19348578
  • Original publications

  • 10891066,9139923