mhqR [Wed Jan 06 2016 11:02:48 GMT+0100 (CET)]

MarR-family transcriptional repressor of azoR2, mhqA, mhqD-mhqE and mhqN-mhqO-mhqP expression

locus: BSU13670

pI: 6.00

mw: 16.00 kDa

function: regulation of resistance to quinones and diamide

product: MarR-family transcriptional repressor

essential: no

synonyms: ykvE

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|transcription factors and their control], [SW|resistance against oxidative and electrophile stress]

Gene

Coordinates on the chromosome (coding sequence): 1,433,199 -> 1,433,636

Phenotypes of a mutant

• resistant to quinones and diamide
• inactivation of ''mhqR'' predisposes cells to grow without a wall (due to protection from oxidative stress) [Pubmed|26051891]

The protein

Additional information

• '''Binding site:''' tATCTcgaAtTCgAGATaaaa [Pubmed|17725564]

Expression and Regulation

Operon

• ''[SW|mhqR]'' [Pubmed|22383849]

Labs working on this gene/protein

• [SW|Haike Antelmann],Free University of Berlin, Germany

References

• 18282125,26051891,17725564,22383849