response regulator aspartate phosphatase (RapE) regulator, control of the phosphorelay
function
control of sporulation initiation
product
phosphatase (RapE) regulator
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.3|Control of response regulators/ other][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.6|Other protein controlling the activity of the phosphorelay][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.6|Other protein controlling the activity of the phosphorelay][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element][category|SW 6|Groups of genes] → [category|SW 6.8|Short peptides][SW|Categories] containing this gene/protein
[SW|phosphorelay], [SW|quorum sensing], [SW|Skin element], [SW|short peptides]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|CcpA regulon], [SW|CodY regulon], [SW|ComA regulon], [SW|SigH regulon]The protein
Protein family
phr family (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|rapE]-[protein|search|phrE]'' [Pubmed|11466295,10629174]''[protein|search|phrE]'' [Pubmed|11466295][SW|Sigma factor]
''[protein|search|phrE]'': [protein|search|SigA] [Pubmed|11466295], [protein|search|SigH] [Pubmed|11466295]Regulation
repressed by glucose (10-fold) ([protein|search|CcpA]) [Pubmed|12850135]repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|12618455][protein|search|ComA]: transcription activation [Pubmed|10629174]Regulatory mechanism
[protein|search|CcpA]: transcription repression[protein|search|CodY]: transcription repression [Pubmed|12618455][protein|search|AbrB]: transcription repression [Pubmed|20817675]References
12618455,12850135,11466295,10629174,21821766,20817675 
