phosphotransferase of the sporulation initiation phosphorelay
function
initiation of sporulation
product
phosphotransferase of the sporulation
initiation phosphorelay
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.3|The phosphotransferases][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.3|The phosphotransferases][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue][SW|Categories] containing this gene/protein
[SW|phosphorelay], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|SigH regulon], [SW|Spo0A regulon]The protein
Modification
phosphorylated on an Asp residue by [protein|search|KinA], [protein|search|KinB], [protein|search|KinC], [protein|search|KinD], or [protein|search|KinE]dephosphorylated by [protein|search|RapA], [protein|search|RapB], [protein|search|RapE], or [protein|search|RapH] [Pubmed|17581123]Structure
[PDB|1SRR] (phosphatase resistant mutant)[PDB|1F51] (complex with [SW|Spo0B])[PDB|2JVK] (Mutant L66A),[PDB|2FSP][PDB|3Q15] ([protein|search|RapH]-[SW|Spo0F] complex) [Pubmed|21346797][SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[SW|Spo0F]-[SW|Spo0B] [Pubmed|12067336][SW|Spo0F]-[SW|Spo0E] [Pubmed|12067336][protein|search|RapA]-[SW|Spo0F] [Pubmed|11923303,22267516][protein|search|RapB]-[SW|Spo0F] [Pubmed|12067336][protein|search|RapE]-[SW|Spo0F][protein|search|RapH]-[SW|Spo0F] [Pubmed|17581123][protein|search|KinA]-[SW|Spo0F][protein|search|KinB]-[SW|Spo0F][protein|search|KinC]-[SW|Spo0F][protein|search|KinD]-[SW|Spo0F][protein|search|KinE]-[SW|Spo0F][protein|search|YmcA]-[SW|Spo0F] [Pubmed|23490197][protein|search|RapP]-[SW|Spo0F], dephosphorylation of [SW|Spo0F] [Pubmed|23524609][protein|search|RapJ]-[SW|Spo0F], dephosphorylation of [SW|Spo0F] [Pubmed|21346797]Expression and Regulation
Operon
''spo0F'' [Pubmed|2457578][SW|Sigma factor]
[protein|search|SigA] [Pubmed|2457578], [protein|search|SigH] [Pubmed|1569009]Regulation
expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|8483422]Regulatory mechanism
[SW|Spo0A]: transcription activation [Pubmed|8483422]References
20413551,9299348,9335530,11923303,8608130,16788205,12067336,8497199,10094672,15299688,8643670,8805550,26165942,11069677,2997779,8483422,16333746,2118512,10997904,9601032,9254596,8730857,10411754,17350627,21346797,9341920,9843420,2509430,1846779,9540996,9477965,17581123,8483422,2457578,1569009,23490197,21346797,22267516,23524609,25598361 
