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oxdC [2017-09-06 13:55:35]
product
oxalate decarboxylase
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.3|Acid stress proteins (controlled by YvrI-YvrHa)][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]Gene
Coordinates
3,410,466 → 3,411,623
The protein
Catalyzed reaction/ biological activity
Oxalate = formate CO2 (according to Swiss-Prot)Paralogous protein(s)
[protein|1568DD457FDD482B3C14954A95F62BE338CBD15D|OxdD]Modification
phosphorylated on Arg-12 [Pubmed|22517742][SW|Cofactors]
requires two Mn(II) centers for activity [Pubmed|24444454,19473032]Structure
[PDB|1L3J] [pubmed|14871895][SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operons
genes
[gene|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]-[gene|07C35D58F6AF97F8E6BB75CF8E8B811BAFAB201B|rsiO]
description
[Pubmed|19047353]
sigma factors
[protein|6359025A73C0BD313F5BCC6F56FE88B820902AAA|SigO]: sigma factor, [Pubmed|19047353], in [regulon|6359025A73C0BD313F5BCC6F56FE88B820902AAA|SigO regulon][protein|AE8D4F07EFB17DA727D80229C3E72075928AA352|RsoA]: sigma factor, in [regulon|AE8D4F07EFB17DA727D80229C3E72075928AA352|RsoA regulon]regulation
induced by acidic growth conditions [Pubmed|19047353]view in new tabBiological materials
Mutant
MGNA-B053 (yvrK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1052 NBRP B. subtilis, Japan]Labs working on this gene/protein
[SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]References
Reviews
Original publications
12056897,18573182,17269748,14871895,10960116,19047353,19473032,11546787,15583401,21264418,21782782,22404040,23734819,25526893,21277974,22517742,24444454,25186982,26641915,26744902,27797181,14871895