oxdC [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

oxalate decarboxylase

locus: BSU33240

pI: 5.00

mw: 43.00 kDa

function: unknown

product: oxalate decarboxylase

essential: no

ec: 4.1.1.2

synonyms: yvrK

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.3|Acid stress proteins (controlled by YvrI-YvrHa)]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]

[SW|Categories] containing this gene/protein

• [SW|acid stress proteins (controlled by SigO-RsoA)], [SW|phosphoproteins]

This gene is a member of the following [SW|regulons]

• [SW|SigO-RsoA regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,410,466 -> 3,411,623

The protein

Catalyzed reaction/ biological activity

• Oxalate = formate CO₂ (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|OxdD]

Modification

• phosphorylated on Arg-12 [Pubmed|22517742]

[SW|Cofactors]

• requires two Mn(II) centers for activity [Pubmed|24444454,19473032]

Structure

• [PDB|1UW8]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|oxdC]-[protein|search|rsiO]'' [Pubmed|19047353]

[SW|Sigma factor]

• [protein|search|SigO]-[SW|RsoA] [Pubmed|19047353]

Regulation

• induced by acidic growth conditions [Pubmed|19047353]

Labs working on this gene/protein

• [SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]

References

Reviews

• 20464388

Original publications

• 12056897,18573182,17269748,14871895,10960116,19047353,19473032,11546787,15583401,21264418,21782782,22404040,23734819,25526893,21277974,22517742,24444454,25186982,26641915,26744902,27797181