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aroF [Mon Aug 31 2015 13:55:18 GMT+0200 (CEST)]

chorismate synthase

locus

BSU22710

6.00

40.00 kDa

function

biosynthesis of aromatic amino acids

product

chorismate synthase

essential

4.2.3.5

synonyms

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.13|Biosynthesis/ acquisition of aromatic amino acids]

[category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]

[SW|Categories] containing this gene/protein

[SW|biosynthesis/ acquisition of amino acids], [SW|phosphoproteins]

Gene

Coordinates on the chromosome (coding sequence)

2,379,100 -> 2,380,272

The protein

Catalyzed reaction/ biological activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate phosphate (according to Swiss-Prot)

Protein family

acetokinase family (according to Swiss-Prot)

Modification

phosphorylated on Arg-127 [Pubmed|22517742]

Structure

[PDB|2O11] (from ''Mycobacterium tuberculosis h37rv mutant'', 42% identity, 58% similarity)

[SW|Localization]

cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operon

References

4202998,22517742