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spoVB [2019-06-06 12:38:49]
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spoVB [2019-06-06 12:38:49]

MurJ family lipid II flippase, spore cortex peptidoglycan synthesis
locus
BSU27670
pI
10.19
mw
55.91 kDa
protein length
518 aa Sequence Blast
gene length
1557 bp Sequence Blast
function
spore cortex peptidoglycan synthesis
product
sporulation-specific MurJ family lipid II flippase
essential
no
synonyms
spoIIIF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    2,829,564 2,831,120

    The protein

    Protein family

  • [SW|Polysaccharide synthase family] (according to UniProt)
  • [SW|MOP exporter family]

    • Paralogous protein(s)

  • [protein|D6B1837075ECBEE1FEAC704DDB6795336092897F|YabM], [protein|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|MurJ], [protein|34A5CD28A3DBCB10B4E1C82E50143FA73B553919|YkvU]

    • Expression and Regulation

    Operons

    genes
    [gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]-[gene|C52461A2FE856C94E0D0701FB7412368404FC83B|yrzE]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [pubmed|1744050], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulatory mechanism

  • [protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID]: repression, [pubmed|15383836], in [regulon|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID regulon]

    • regulation

  • expressed early during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE], [SW|SpoIIID]) [Pubmed|1744050,15383836]
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    Biological materials

    Mutant

  • BKE27670 ([gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC, downstream forward: _UP4_GGACGGTTGATCATCCGATA
  • BKK27670 ([gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC, downstream forward: _UP4_GGACGGTTGATCATCCGATA

    • References

  • 19648239,19666716,1744050,15383836,25918422