dhbF [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

involved in 2,3-dihydroxybenzoate biosynthesis

Locus: BSU31960

Isoelectric point: 4.00

Molecular weight: 263.00 kDa

Function: biosynthesis of the siderophore bacillibactin

Product: unknown

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Homeostasis → Acquisition of iron → Acquisition of iron / Other
• Metabolism → Additional metabolic pathways → Iron metabolism → Acquisition of iron / Other
• Groups of genes → Membrane proteins
• Groups of genes → Phosphoproteins → Phosphorylation on a Ser residue

Categories containing this gene/protein

• acquisition of iron, iron metabolism, membrane proteins, phosphoproteins

This gene is a member of the following regulons

• AbrB regulon, Fur regulon, Kre regulon

Gene

Coordinates on the chromosome (coding sequence): 3,280,519 -> 3,287,655

The protein

Protein family

• ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)

Modification

• phosphorylation on Ser-988 AND Ser-996 PubMed

Localization

• membrane PubMed

Expression and Regulation

Operon

• dhbA-dhbC-dhbE-dhbB-dhbF PubMed

Sigma factor

• SigA PubMed

Regulation

• induced by iron starvation (Fur) PubMed

Regulatory mechanism

• Fur: transcription repression PubMed
• AbrB: transcription repression PubMed

Additional information

• the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] PubMed
• the dhbA-dhbC-dhbE-dhbB-dhbF operon is strongly unregulated in a kre mutant PubMed

References

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