dgkB [Tue Feb 14 2017 12:30:33 GMT+0100 (CET)]

diacylglycerol kinase

locus: BSU06720

pI: 5.00

mw: 33.00 kDa

function: biosynthesis of lipoteichoic acid

product: diacylglycerol kinase

essential: no

ec: 2.7.1.107

synonyms: yerQ

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.3|Biosynthesis of lipoteichoic acid]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.2|Biosynthesis of lipoteichoic acid]

[SW|Categories] containing this gene/protein

• [SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence): 736,436 -> 737,347

Phenotypes of a mutant

• essential [Pubmed|12682299], non-essential according to [Pubmed|28189581]

The protein

Paralogous protein(s)

• [protein|search|BmrU]

Structure

• [PDB|3S40] (from ''B. anthracis'', 32% identity, 68% similarity)

Biological materials

Mutant

• MGNA-B448 (yerQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1447 NBRP B. subtilis, Japan]
• GP1391 ''dgkB::cat ltaS::aphA3'', available in [SW|Jörg Stülke]'s lab

References

Reviews

• 24819367

Original publications

• 17535816,22451476,28189581