SubtiBank SubtiBank
tcyB
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tcyB

cystine and diaminopimelate ABC transporter (permease)
Locus
BSU_03600
Isoelectric point
9.93
Molecular weight
26.24 kDa
Protein length
234 aa Sequence Blast
Gene length
705 bp Sequence Blast
Function
cystine and diaminopimelate uptake
Product
cystine and diaminopimelate ABC transporter (permease), membrane protein
Essential
no
Synonyms
yckJ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → ABC transporters → Importers → Uptake of amino acids
  • Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of cysteine
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    409,965 410,669

    The protein

    Catalyzed reaction/ biological activity

  • uptake of cystine and diaminopimelate PubMed

    • Protein family

  • Binding-protein-dependent transport system permease family (according to UniProt)

    • Paralogous protein(s)

  • YxeN, YckA

    • Structure

  • 4YMS (amino acid transporter from Caldanaerobacter subterraneus, 37% identity) PubMed

    • Localization

  • membrane protein PubMed

    • Expression and Regulation

    Operons

    Genes
    tcyA-tcyB-tcyC
    Description
    PubMed

    Regulation

  • strongly repressed in response to glucose starvation in M9 medium PubMed
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    Biological materials

    Mutant

  • MGNA-C059 (yckJ::erm), available at the NBRP B. subtilis, Japan
  • BKE03600 (tcyB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CGTGCCAAGCGTCAATGCCG, downstream forward: _UP4_GTGGCCAAATAAGGAGGTTC
  • BKK03600 (tcyB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CGTGCCAAGCGTCAATGCCG, downstream forward: _UP4_GTGGCCAAATAAGGAGGTTC

    • References

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