mtnE [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

glutamine transaminase

locus: BSU13580

pI: 4.91

mw: 43.00 kDa

function: methionine salvage

product: glutamine transaminase

essential: no

synonyms: ykrV

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.10|Biosynthesis/ acquisition of methionine/ S-adenosylmethionine]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of amino acids]

Gene

Coordinates on the chromosome (coding sequence): 1,425,641 -> 1,426,837

Phenotypes of a mutant

• reduced growth with 5-methylthioribose as single sulfur source [Pubmed|24837359]

The protein

Catalyzed reaction/ biological activity

• 2-ketomethylthiobutyrate + glutamine ---> 2-ketoglutaramate + methionine [Pubmed|24837359]

Protein family

• MtnE subfamily (according to Swiss-Prot)

[SW|Interactions]

• forms dimers [Pubmed|24837359]

Expression and Regulation

Operon

• ''mtnE'' [Pubmed|12022921]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|12022921]

References

• 12670965,15102328,12022921,24837359