yhcA [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

similar to multidrug resistance protein

locus: BSU09010

pI: 9.49

mw: 58.00 kDa

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.11|Other exporters]
• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.3|Metabolism of signalling nucleotides]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 977,775 -> 979,373

The protein

Protein family

• EmrB family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|LmrB], [protein|search|YcnB]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|yhbI]-[protein|search|yhbJ]-[protein|search|yhcA]-[protein|search|yhcB]-[protein|search|yhcC]-[protein|search|yhcD]-[protein|search|yhcE]-[protein|search|yhcF]-[protein|search|yhcG]-[protein|search|yhcH]-[protein|search|yhcI]'' [Pubmed|21815947]

Additional information

• the mRNA is substantially stabilized upon depletion of [Rny|search|RNase Y] (the half-life of the mRNA increases from 4 to 41 min) [PubMed|21815947]

Biological materials

Mutant

• GP1704 (''[protein|search|yhcA]''::''ermC'', without terminator), available in [SW|Jörg Stülke]'s lab

References

• 21815947