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proI [2017-07-30 17:22:46]
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proI [2017-07-30 17:22:46]

pyrroline-5-carboxylate reductase
Locus
BSU23800
Isoelectric point
6.70
Molecular weight
30.24 kDa
Protein length
278 aa Sequence Blast
Gene length
834 bp Sequence Blast
Function
biosynthesis of proline
Product
pyrroline-5-carboxylate reductase
Essential
no
E.C.
1.5.1.2
Synonyms
yqjO
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of proline

    • Gene

    Coordinates
    2,473,151 → 2,473,987

    The protein

    Catalyzed reaction/ biological activity

  • L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H (according to Swiss-Prot)

    • Protein family

  • pyrroline-5-carboxylate reductase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • ProH

    • Expression and Regulation

    Operons

    Genes
    proI
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • T-box: anti-termination, in T-box

    • Regulation

  • induced by proline limitation (T-box) PubMed
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    Biological materials

    Mutant

  • MGNA-C395 (yqjO::erm), available at the NBRP B. subtilis, Japan

    • References

    Reviews

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    Original publications

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