rsbP [2019-03-12 18:44:08]

protein serine phosphatase, energy PP2C, dephosphorylates RsbV

Locus: BSU34110

Isoelectric point: 4.83

Molecular weight: 45.87 kDa

Protein length: 403 aa

Gene length: 1212 bp

Function: control of SigB activity

Product: protein serine phosphatase, energy PP2C

Essential: no

E.C.: 3.1.3.3

Synonyms: yvfP

Genomic Context

Loading

Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Protein modification → Protein phosphatases
• Information processing → Regulation of gene expression → Sigma factors and their control → Control of sigma factors

Gene

Coordinates: 3,500,386 3,501,597

The protein

Catalyzed reaction/ biological activity

• dephosphorylation of RsbV in response to red light, this results in SigB activation PubMed

Domains

• N-terminal PAS domain, central coiled-coil domain, C-terminal PP2C phosphatase domain

Effectors of protein activity

• activity is stimulated upon interaction of the RsbP oligomer with RsbQ PubMed

Expression and Regulation

Operons

• Genes: rsbP-rsbQ
  Description: PubMed

Biological materials

Mutant

• MGNA-A488 (yvfP::erm), available at the NBRP B. subtilis, Japan
• BKE34110 (rsbP::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTAAGAGGGTCACCTCT, downstream forward: _UP4_TAAAATGATCCATGAGACAT
• BKK34110 (rsbP::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTAAGAGGGTCACCTCT, downstream forward: _UP4_TAAAATGATCCATGAGACAT

Labs working on this gene/protein

• Chet Price, Davis, USA homepage

References

Reviews

Loading

Original publications

Loading