SubtiBank SubtiBank
yqxC [2019-03-19 19:16:18]
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yqxC [2019-03-19 19:16:18]

similar to rRNA methyltransferase
locus
BSU24260
pI
10.11
mw
29.50 kDa
protein length
281 aa Sequence Blast
gene length
846 bp Sequence Blast
function
unknown
product
putative rRNA methyltransferase
essential
no
synonyms
yqiF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.3|rRNA modification and maturation/ based on similarity]

    • Gene

    Coordinates
    2,522,871 2,523,716

    The protein

    [SW|Cofactors]

  • SAM [pubmed|28031456]

    • Structure

  • [PDB|3HP7] (from Streptococcus thermophilus, 60% identity)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]
    description
    [Pubmed|2507400]

    additional information

  • the terminator is [protein|search|NusA]-dependent [ http://www.nature.com/articles/nmicrobiol20157 Reference]
    • view in new tab

    genes
    [gene|EA9FCF84AE4FA80993566B62A9200D4B32AF5670|dxs]-[gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]-[gene|62F8E0D6BC9DA6390256FA8FB684EA5C9C722AE4|ahrC]-[gene|5680A06A74D3EC6310EF8677795511C75DB3059E|recN]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, [pubmed|11948165], in [regulon|stringent response|stringent response]

    • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
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    Biological materials

    Mutant

  • MGNA-C369 (yqxC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2367 NBRP B. subtilis, Japan]
  • BKE24260 ([gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE24260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCTAATCGTTCTTTCTTTG, downstream forward: _UP4_TAATAGGGCGCTATTATTCC
  • BKK24260 ([gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK24260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCTAATCGTTCTTTCTTTG, downstream forward: _UP4_TAATAGGGCGCTATTATTCC

    • References

  • 2507400,28031456,20854656,21443791