yqxC

similar to rRNA methyltransferase

Locus: BSU_24260

Isoelectric point: 10.11

Molecular weight: 29.50 kDa

Protein length: 281 aa

Gene length: 846 bp

Function: unknown

Product: putative rRNA methyltransferase

Essential: no

Synonyms: yqiF

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Translation → rRNA modification and maturation/ based on similarity

Gene

Coordinates: 2,522,871 2,523,716

The protein

Protein family

• S4 RNA-binding domain superfamily (according to http://www.ebi.ac.uk/interpro/entry/IPR036986 Interpro)
• TlyA family (single member, according to UniProt)

Domains

• S4 RNA-binding domain (aa 6-67) (according to UniProt)

Cofactors

• SAM PubMed

Structure

• 3HP7 (from Streptococcus thermophilus, 60% identity)

Localization

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: yqxC
  Description: PubMed

  Additional information

  • the terminator is NusA-dependent [ http://www.nature.com/articles/nmicrobiol20157 Reference]

• Genes: dxs-yqxC-ahrC-recN
  Description: PubMed

  Regulatory mechanism

  • stringent response: negative regulation, PubMed, in stringent response

  Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed

Biological materials

Mutant

• MGNA-C369 (yqxC::erm), available at the NBRP B. subtilis, Japan
• BKE24260 (yqxC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATCTAATCGTTCTTTCTTTG, downstream forward: _UP4_TAATAGGGCGCTATTATTCC
• BKK24260 (yqxC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATCTAATCGTTCTTTCTTTG, downstream forward: _UP4_TAATAGGGCGCTATTATTCC

References

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